Space Seed was on this morning. I love this exchange with a newly-awakened Khan.
Bones: Well, either choke me or cut my throat. Make up your mind.
Khan: Where am I?
Bones: You're in bed, holding a knife at your doctor's throat.
Dr. Leonard McCoy has so meditated upon the Tao of the Grumpy Old Man that when confronted by a megalomaniacal ubermensch with a knife he's able to turn his crankiness into an impenetrable shield of badassery. Respect the Bones.